DeCS Server - List Exact Term

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DeCS

Descriptor English:

F-Box-WD Repeat-Containing Protein 7

Descriptor Spanish:

Proteína 7 que Contiene Repeticiones F-Box-WD

Descriptor Portuguese:

Proteína 7 com Repetições F-Box-WD

Synonyms English:

F-Box and WD-40 Domain-Containing Protein 7
FBXW7 Protein
F Box WD Repeat Containing Protein 7
F Box and WD 40 Domain Containing Protein 7

Tree Number:

Definition English:

A component of SCF(FBW7) UBIQUITIN LIGASE that contains an F-box motif and multiple WD REPEATS. It recognizes and binds phosphorylated signals in several proteins involved in CELL PROLIFERATION and targets them to the SCF complex for UBIQUITINATION. Targets include CYCLIN E; PROTO-ONCOGENE PROTEINS C-JUN; PROTO-ONCOGENE PROTEINS C-MYC; and JNK MITOGEN-ACTIVATED PROTEIN KINASES.

History Note English:

2018

Allowable Qualifiers English:

Record Number:

57012

Unique Identifier:

D000073979

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